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Hot-melt extrusion in Food and Pharma

Reactor Systems

Hot-melt extrusion (HME) is an emerging technology for the continuous manufacture of drugs within the pharmaceutical industry, with proven robustness for numerous drug delivery systems. One key advantage is the ability to produce a variety of formulations, such as solid dose forms, which improve drug bioavailability. HME is a solvent-free, continuous process. It is in fact a simplification of complex, multi-stage processes.
Improve your drug bioavailability with a solvent-free, continuous process.

HME in Food and Pharma

Tablets and capsules are currently the most popular oral solid dosage form in the pharmaceutical industry. Tablets and capsules with fine particles of the active product, give a significantly faster dissolution. These particles can be added in the form of micro pellets.

Pellets are not powder and not granulate; they are characterized by a defined shape and a very narrow particle size distribution. This allows a very wide range of applications of pellets that integrate active substances.

Employing hot-melt / melt extrusion, even the processing of poorly soluble carrier/active substance combinations, no longer poses a major problem in the pharmaceutical industry. Continuous manufacturing delivers many benefits in production and in speeding up the development cycles for new drugs.

MAAG offers a wide range of products for hot-melt extrusion in food and pharma. Depending on the desired process we have several products that can meet the customers’ requirements.

MAAG systems all comply with the regulations in food & pharma industries.

Advantages of the MAAG systems

  • Homogeneous, consistent particle/pellet sizes
  • Production of micro pellets ≥ 0,3 mm
  • Continuous manufacturing
  • Simplification of complex, multi-stage processes
  • No grinding required
  • No/ much less dust created than with conventional methods
  • Simple scale-up of your process
  • For pelletizing directly from an extruder or reactor vessel

Suurmond supplies solutions to optimize your process and improve the quality of your end-product. Our specialists will be happy to advise you.

Let's talk!

Hot-melt extrusion in Food and Pharma

Production of micro pellets for food & pharma.

Let's talk!

Suurmond BV
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Suurmond BV
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69400 Limas
info.fr@suurmond.com

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